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Alzheimer’s News: Depression Molecule Helps Improve Memory in Alzheimer


September 12, 2019 0):?> in: Memory Care (dementia/alzheimers) Uncategorized

It's always welcome news when the advancements of science yield encouraging and amazing discoveries. In this case, the information could help improve memory in Alzheimer patients, and the disease could certainly use some hopeful headlines.

The statistics paint a sobering view of the condition. For example, an estimated 5.8 million Americans are living with Alzheimer's disease in 2019. This includes all ages. Also, some 44 million people globally have Alzheimer's or related dementia.

But there may be a therapeutic molecule that appears to reverse memory loss associated with depression and aging. That's not all. The research has also revealed that the molecule can quickly improve symptoms of the disease and repair the brain dysfunction that is causing memory loss.

The special molecule drug was created at Toronto's Centre for Addiction and Mental Health (CAMH). A dose of the molecules was invented to bind to and activate damaged brain cell receptors. Chemists are studying the drug, but it's still in the experimental stages and is not yet available to patients. In fact, lead scientists of the study will not begin testing the molecules in human clinical research until two years from now.

However, the early results from the testing of preclinical models of stress-induced memory loss are impressive, according to reports in ScienceDaily.com. For instance, after a single dose was administered, it took only 30 minutes for the brain to recover and return memory performance to normal levels.

Another preclinical model testing experiment involved that of aging. Declining memories were given a dose of the molecules, and incredible results were discovered. Performance improved by 80 percent, and the memory was reversed back to a level of youth or early adulthood. In addition, daily treatment of the molecule drug delivered long-lasting effects of two months.

The scientist leading the charge on the new molecule invention is Dr. Etienne Sibille, Deputy Director of the Campbell Family Mental Health Research Institute at CAMH. Sibille says it's very difficult developing proper medications to treat memory loss associated with Alzheimer's disease, depression and other mental illnesses. He is hopeful that the new drug could eventually be given in pill form to patients who are at risk of such cognitive problems. Sibille says that patients in their late 50s would be the ideal age for starting the treatment.

So far, the molecule drug has only been tested on mice, but Sibille believes the drug would also be safe and effective for people and improve memory in Alzheimer sufferers.

Sibille is excited by the findings and told the media that the drug could actually modify the brain. "The aged cells regrew to appear the same as young brain cells."

For a drug to improve memory in Alzheimer patients and those with depression and more, this could be the breakthrough treatment the world has been waiting for.

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